Normal triglyceride levels despite insulin resistance in African Americans: role of lipoprotein lipase.

@article{Sumner2005NormalTL,
  title={Normal triglyceride levels despite insulin resistance in African Americans: role of lipoprotein lipase.},
  author={Anne E. Sumner and Gloria Lena Vega and David J Genovese and Karl B Finley and Richard N Bergman and Raymond C. Boston},
  journal={Metabolism: clinical and experimental},
  year={2005},
  volume={54 7},
  pages={902-9}
}
Abstract Lipoprotein lipase (LPL), the enzyme responsible for hydrolyzing triglyceride (TG) in plasma lipoproteins, is a key regulator of plasma TG levels. In Caucasians, postheparin-LPL (PH-LPL) activity is impaired in the presence of insulin resistance and leads to elevated TG levels. However, African Americans are often both insulin-resistant and normotriglyceridemic. But in African Americans, the effect of insulin resistance on PH-LPL activity has not been studied. In African Americans, if… CONTINUE READING
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