Normal striatal D2 receptor binding in idiopathic restless legs syndrome with periodic leg movements in sleep.

@article{Tribl2004NormalSD,
  title={Normal striatal D2 receptor binding in idiopathic restless legs syndrome with periodic leg movements in sleep.},
  author={Gotthard G Tribl and Susanne Asenbaum and Svenja Happe and Raphael Maria Bonelli and Josef Zeitlhofer and Eduard Auff},
  journal={Nuclear medicine communications},
  year={2004},
  volume={25 1},
  pages={55-60}
}
Dopaminergic treatment is very effective in restless legs syndrome (RLS) and periodic leg movements in sleep (PLMS). However, neuroreceptor imaging studies that addressed altered striatal dopaminergic function have given controversial results. In this present study, 14 patients with idiopathic RLS (iRLS) and PLMS with a good response to dopaminergic and non-dopaminergic treatment and ten healthy sex- and age-matched controls were investigated off-medication by using 123I-IBZM and SPECT. RLS… CONTINUE READING

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Restless legs syndrome.

Neurologic clinics • 2009

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