Normal-sodium diet compared with low-sodium diet in compensated congestive heart failure: is sodium an old enemy or a new friend?

@article{Paterna2008NormalsodiumDC,
  title={Normal-sodium diet compared with low-sodium diet in compensated congestive heart failure: is sodium an old enemy or a new friend?},
  author={Salvatore Paterna and Parrinello Gaspare and Sergio Fasullo and Filippo M Sarullo and Pietro di Pasquale},
  journal={Clinical science},
  year={2008},
  volume={114 3},
  pages={
          221-30
        }
}
The aim of the present study was to evaluate the effects of a normal-sodium (120 mmol sodium) diet compared with a low-sodium diet (80 mmol sodium) on readmissions for CHF (congestive heart failure) during 180 days of follow-up in compensated patients with CHF. A total of 232 compensated CHF patients (88 female and 144 male; New York Heart Association class II-IV; 55-83 years of age, ejection fraction <35% and serum creatinine <2 mg/dl) were randomized into two groups: group 1 contained 118… Expand
A normal sodium diet preserves serum sodium levels during treatment of acute decompensated heart failure: A prospective, blind and randomized trial.
TLDR
It is suggested that a normal sodium diet, when compared to a low Sodium diet, is associated with similar degrees of decongestion, but with higher levels of natremia, blood pressure and lower neurohormonal activation during ADHF treatment. Expand
Medium term effects of different dosage of diuretic, sodium, and fluid administration on neurohormonal and clinical outcome in patients with recently compensated heart failure.
TLDR
The data suggest that the combination of a normal-sodium diet with high diuretic doses and fluid intake restriction, compared with different combinations of sodium diets with more modest fluid intake restrictions and conventional diUREtic doses, leads to reductions in readmissions, neurohormonal activation, and renal dysfunction. Expand
Low- Versus Moderate-Sodium Diet in Patients With Recent Hospitalization for Heart Failure: The PROHIBIT (Prevent Adverse Outcomes in Heart Failure by Limiting Sodium) Pilot Study.
TLDR
Because both diets reduced urinary sodium without adverse safety or quality of life signals, a larger trial, with modifications to improve participation and compliance, would be ethical and feasible. Expand
The long-term effects of dietary sodium restriction on clinical outcomes in patients with heart failure. The SODIUM-HF (Study of Dietary Intervention Under 100 mmol in Heart Failure): a pilot study.
TLDR
A dietary intervention restricting sodium intake was feasible, and achievement of this sodium goal was associated with lower BNP levels and improved quality of life in patients with HF. Expand
A high-sodium diet is associated with acute decompensated heart failure in ambulatory heart failure patients: a prospective follow-up study.
TLDR
This study provides the first prospective evidence that ambulatory HF patients who consume higher amounts of sodium are at greater risk of an ADHF event, and provides support for more stringent sodium intake guidelines than those currently recommended for HF patients. Expand
Nutritional inadequacies in patients with stable heart failure.
TLDR
In stable patients with heart failure, sodium intake was not excessive, however, widespread dietary inadequacies of other vitamins and minerals were demonstrated, highlighting the importance of diet beyond that of sodium restriction. Expand
Short-Term Effects of Hypertonic Saline Solution in Acute Heart Failure and Long-Term Effects of a Moderate Sodium Restriction in Patients With Compensated Heart Failure With New York Heart Association Class III (Class C) (SMAC-HF Study)
TLDR
It is suggested that in-hospital HSS administration, combined with moderate Na restriction, reduces hospitalization time and that a moderate sodium diet restriction determines long-term benefit in patients with NYHA class III HF. Expand
Dietary sodium restriction below 2 g per day predicted shorter event-free survival in patients with mild heart failure
TLDR
Sodium restriction below 2 g/ day is not warranted in mild HF patients, whereas excessive sodium intake above 3 g/day may be harmful in moderate to severe HF patients. Expand
Effect of fluid and dietary sodium restriction in the management of patients with heart failure and preserved ejection fraction: study protocol for a randomized controlled trial
TLDR
Assessment of the effects of sodium and fluid restriction on neurohormonal activation and clinical course of HF-PEF can promote a deeper understanding of the pathophysiology and progression of this complex syndrome. Expand
Effects of low-sodium diet vs. high-sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride (Cochrane Review).
TLDR
Sodium reduction resulted in a significant decrease in BP of 1% (normotensives), and a significant increase in plasma renin, plasma aldosterone, plasma adrenaline, and plasma noradrenaline, a 2.5% increase in cholesterol, and a 7% increases in triglyceride. Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 57 REFERENCES
Abnormalities of Sodium Handling and of Cardiovascular Adaptations During High Salt Diet in Patients With Mild Heart Failure
TLDR
Results show a reduced ability to excrete a sodium load and early abnormalities of cardiac and hemodynamic adaptations to salt excess in patients with mild heart failure and no signs or symptoms of congestion. Expand
Sodium and water balance in chronic congestive heart failure.
TLDR
Renin-angiotensin system activity was significantly higher in the second subgroups of response to the 100 meq diet, and the mechanism for differences in sodium excretion for the subgroups could not be identified by blood volume or hemodynamic parameters. Expand
Effects of acetylsalicylic acid on renal function in patients with chronic heart failure.
TLDR
It is concluded that severe sodium depletion has adverse effects on kidney function in patients with heart failure due to a reduction in the glomerular filtration rate. Expand
Hemodynamic and neuroendocrine responses to changes in sodium intake in compensated heart failure.
TLDR
The observation that high sodium intake improves cardiac performance, induces peripheral vasodilatation, and suppresses the release of vasoconstrictor hormones does not support the advice for HF patients to restrict dietary sodium. Expand
Changes in brain natriuretic peptide levels and bioelectrical impedance measurements after treatment with high-dose furosemide and hypertonic saline solution versus high-dose furosemide alone in refractory congestive heart failure: a double-blind study.
TLDR
The data show that the HSS group reached dry weight more rapidly, a significantly faster reduction in BNP levels, shorter hospitalization stay, and lower incidence in readmissions in the 30-day study period. Expand
High-Dose Torasemide is Equivalent to High-Dose Furosemide with Hypertonic Saline in the Treatment of Refractory Congestive Heart Failure
TLDR
High-dose torasemide is equivalent to high-dose furosemide in the treatment of refractory CHF, and a significant increase in daily diuresis and natriuresis was observed in both groups. Expand
Effects of high-dose furosemide and small-volume hypertonic saline solution infusion in comparison with a high dose of furosemide as bolus in refractory congestive heart failure: long-term effects.
TLDR
A randomized, single-blind study was performed to evaluate the effects of the combination of high-dose furosemide and small-volume hypertonic saline solution (HSS) infusion in the treatment of refractory New York Heart Association class IV CHF and a normosodic diet during follow-up. Expand
Small-Volume Hypertonic Saline Solution and High-Dosage Furosemide in the Treatment of Refractory Congestive Heart Failure
TLDR
Findings suggest that this new therapeutic approach to refractory CHF is effective and well tolerated and should represent an innovative tool for the management of refractor CHF. Expand
Lower Serum Sodium Is Associated With Increased Short-Term Mortality in Hospitalized Patients With Worsening Heart Failure: Results From the Outcomes of a Prospective Trial of Intravenous Milrinone for Exacerbations of Chronic Heart Failure (OPTIME-CHF) Study
TLDR
In patients hospitalized for worsening heart failure, admission serum sodium is an independent predictor of increased number of days hospitalized for cardiovascular causes and increased mortality within 60 days of discharge. Expand
High dietary sodium chloride consumption may not induce body fluid retention in humans.
TLDR
It is concluded from the results of these two independently conducted studies that under the chosen study conditions, high sodium intake does not induce total body water storage but induces a relative fluid shift from the interstitial into the intravascular space. Expand
...
1
2
3
4
5
...