Normal retina releases a diffusible factor stimulating cone survival in the retinal degeneration mouse.

@article{MohandSaid1998NormalRR,
  title={Normal retina releases a diffusible factor stimulating cone survival in the retinal degeneration mouse.},
  author={Saddek Mohand-Said and A Deudon-Combe and David W. Hicks and Manuel Simonutti and Val{\'e}rie Forster and Anne Claire Fintz and Thierry L{\'e}veillard and Henri Dreyfus and Jos{\'e} Alain Sahel},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1998},
  volume={95 14},
  pages={8357-62}
}
The role of cellular interactions in the mechanism of secondary cone photoreceptor degeneration in inherited retinal degenerations in which the mutation specifically affects rod photoreceptors was studied. We developed an organ culture model of whole retinas from 5-week-old mice carrying the retinal degeneration mutation, which at this age contain few remaining rods and numerous surviving cones cocultured with primary cultures of mixed cells from postnatal day 8 normal-sighted mice (C57BL/6… CONTINUE READING
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