Normal perfusion pressure breakthrough: the role of capillaries.

  title={Normal perfusion pressure breakthrough: the role of capillaries.},
  author={Lali H. S. Sekhon and Michael Kerin Morgan and I. Spence},
  journal={Journal of neurosurgery},
  volume={86 3},
Excision of human cerebral arteriovenous malformations (AVMs) can be complicated by postoperative edema and hemorrhage in adjacent brain tissue, despite the complete excision of the malformation. Various theories have purported to explain the hemodynamic basis for this predisposition, including disordered autoregulation causing "normal perfusion pressure breakthrough" and obstruction of venous drainage leading to "occlusive hyperemia." This study did not evaluate the arterial or venous… CONTINUE READING


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