Normal left-atrial structure and function despite concentric left-ventricular remodelling in a cohort of patients with Anderson-Fabry disease.

@article{Putko2015NormalLS,
  title={Normal left-atrial structure and function despite concentric left-ventricular remodelling in a cohort of patients with Anderson-Fabry disease.},
  author={Brendan N. Putko and Haran Yogasundaram and Kelvin Chow and Joseph J Pagano and Aneal A Khan and David Ian Paterson and Richard F. Thompson and Gavin Yadram Oudit},
  journal={European heart journal cardiovascular Imaging},
  year={2015},
  volume={16 10},
  pages={1129-36}
}
AIMS Anderson-Fabry Disease (AFD) is an important cause of cardiomyopathy characterized by concentric left-ventricular hypertrophy (LVH). We evaluated the extent of left-atrial (LA) structural and functional remodelling in this group of patients given that LA remodelling is a marker of adverse outcomes in the presence of LVH. METHODS AND RESULTS Clinical profiles were obtained and cardiac MRI was performed in cohorts of patients with AFD (n = 31), healthy controls (n = 23), and a positive… CONTINUE READING