Normal functional protein S activity does not exclude protein S deficiency.

@article{Rodger2003NormalFP,
  title={Normal functional protein S activity does not exclude protein S deficiency.},
  author={Marc A Rodger and Marc Carrier and Muriel Gervais and G. Rock},
  journal={Pathophysiology of haemostasis and thrombosis},
  year={2003},
  volume={33 4},
  pages={202-5}
}
Protein S (PS) deficiency appears to increase the risk of venous thrombosis. PS deficiency is classified into three phenotypes using antigenic levels and functional activity. By definition, all three phenotypes of PS deficiency should result in low activated protein C cofactor activity. We compared the results of functional PS activity testing to free antigenic PS testing in order to determine if a normal functional PS activity assay result could eliminate the need for free antigenic PS testing… CONTINUE READING