Normal-appearing white matter changes vary with distance to lesions in multiple sclerosis.

Abstract

BACKGROUND AND PURPOSE Multiple sclerosis (MS) disease processes in normal-appearing white matter (NAWM) may be different close to MR-visible lesions than farther from these lesions. We aimed to investigate the relationship of NAWM changes to the distance to the lesions. METHODS We measured B(1)-corrected T1 and magnetization transfer ratio (MTR) maps in… (More)

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