Normal Performance of Fmr1 Mice on a Touchscreen Delayed Nonmatching to Position Working Memory Task.

Abstract

Fragile X syndrome is a neurodevelopmental disorder characterized by mild-to-severe cognitive deficits. The complete absence of Fmr1 and its protein product in the mouse model of fragile X (Fmr1 KO) provides construct validity. A major conundrum in the field is the remarkably normal performance of Fmr1 mice on cognitive tests in most reports. One… (More)
DOI: 10.1523/ENEURO.0143-15.2016

Topics

11 Figures and Tables

Cite this paper

@article{Leach2016NormalPO, title={Normal Performance of Fmr1 Mice on a Touchscreen Delayed Nonmatching to Position Working Memory Task.}, author={Prescott T. Leach and Jane Hayes and Michael C. Pride and Jill L. Silverman and Jacqueline N. Crawley}, journal={eNeuro}, year={2016}, volume={3 1} }