Norfriedelins A-C with acetylcholinesterase inhibitory activity from acerola tree (Malpighia emarginata).

  title={Norfriedelins A-C with acetylcholinesterase inhibitory activity from acerola tree (Malpighia emarginata).},
  author={Jie-Qing Liu and Xingrong Peng and Xu-Yang Li and Ting-zhao Li and Wei-Ming Zhang and Lei Shi and Jiang Han and Minghua Qiu},
  journal={Organic letters},
  volume={15 7},
Three novel norfriedelanes, A-C (1-3), were isolated from the branches and roots of Malpighia emarginata . Their structures and absolute configurations were determined by 1D and 2D NMR techniques and X-ray crystallographic analysis. Norfriedelin A (possessing an α-oxo-β-lactone group) and norfriedelin B (with a keto-lactone group) showed acetylcholinesterase inhibitory effects with the IC50 values of 10.3 and 28.7 μM, respectively. 

Monoterpene esters and aporphine alkaloids from Illigera aromatica with inhibitory effects against cholinesterase and NO production in LPS-stimulated RAW264.7 macrophages

The chemical structure and bioactive foundation for using I. aromatica as an herbal medicine is provided and four new monoterpene phenylpropionic acid esters and one new aporphine alkaloid, illigeranine, are identified.

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