Norepinephrine turnover in the heart and spleen of the cardiomyopathic Syrian hamster.

@article{Sole1975NorepinephrineTI,
  title={Norepinephrine turnover in the heart and spleen of the cardiomyopathic Syrian hamster.},
  author={Michael Sole and C M Lo and Cameron Laird and Edmund H. Sonnenblick and R. J. Wurtman},
  journal={Circulation research},
  year={1975},
  volume={37 6},
  pages={855-62}
}
Although a reduction in myocardial norepinephrine stores in cardiac hypertrophy and congestive failure is well documented, norepinephrine turnover has been inadequately studied in such hearts. We compared norepinephrine turnover in control and cardiomyopathic hamsters by following the decline in specific activity of myocardial norepinephrine after labelling with an intraperitoneal tracer dose of 3H-norepinephrine. Adult myocardial norepinephrine concentrations were not attained until 4 weeks of… CONTINUE READING

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