Norepinephrine turnover in the heart and spleen of the cardiomyopathic Syrian hamster.

  title={Norepinephrine turnover in the heart and spleen of the cardiomyopathic Syrian hamster.},
  author={Michael Sole and C M Lo and Cameron Laird and Edmund H. Sonnenblick and R. J. Wurtman},
  journal={Circulation research},
  volume={37 6},
Although a reduction in myocardial norepinephrine stores in cardiac hypertrophy and congestive failure is well documented, norepinephrine turnover has been inadequately studied in such hearts. We compared norepinephrine turnover in control and cardiomyopathic hamsters by following the decline in specific activity of myocardial norepinephrine after labelling with an intraperitoneal tracer dose of 3H-norepinephrine. Adult myocardial norepinephrine concentrations were not attained until 4 weeks of… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 30 extracted citations

Idiopathic Dilated Cardiomyopathy

Springer Berlin Heidelberg • 1993
View 10 Excerpts
Highly Influenced

Norepinephrine turnover in peripheral tissues of rats with heart failure.

American journal of physiology. Regulatory, integrative and comparative physiology • 2000
View 3 Excerpts
Highly Influenced

Introduction to cardiac neuronal imaging: a clinical perspective.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine • 2015
View 2 Excerpts


Publications referenced by this paper.
Showing 1-10 of 18 references

Critical assessment of methods for the determination of monoamine synthesis turnover rates in vivo

Neuropsychopharmacology of Monoamines and Their Regulatory Enzymes • 1974

Postnatal development of myocardial adrenergic mechanisms in the cat (abstr)

Circulation 48(suppl IV):IV-36, • 1973

Intrinsic physiologic properties of the developing heart

Prog Cardiovasc Dis 15:87-111, • 1972

Cardiovascular responses during exertion

Cardiovascular Dynamics • 1970

Similar Papers

Loading similar papers…