Norepinephrine transporter: a candidate gene for initial ethanol sensitivity in inbred long-sleep and short-sleep mice.

@article{Haughey2005NorepinephrineTA,
  title={Norepinephrine transporter: a candidate gene for initial ethanol sensitivity in inbred long-sleep and short-sleep mice.},
  author={Heather M Haughey and Alan L. Kaiser and Thomas Johnson and Beth Bennett and James M. Sikela and Nancy R. Zahniser},
  journal={Alcoholism, clinical and experimental research},
  year={2005},
  volume={29 10},
  pages={1759-68}
}
BACKGROUND Altered noradrenergic neurotransmission is associated with depression and may contribute to drug abuse and alcoholism. Differential initial sensitivity to ethanol is an important predictor of risk for future alcoholism, making the inbred long-sleep (ILS) and inbred short-sleep (ISS) mice a useful model for identifying genes that may contribute to alcoholism. METHODS In this study, molecular biological, neurochemical, and behavioral approaches were used to test the hypothesis that… CONTINUE READING

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