Norepinephrine microinjections in the hypothalamic paraventricular nucleus increase extracellular dopamine and decrease acetylcholine in the nucleus accumbens: relevance to feeding reinforcement.

@article{Hajnal1997NorepinephrineMI,
  title={Norepinephrine microinjections in the hypothalamic paraventricular nucleus increase extracellular dopamine and decrease acetylcholine in the nucleus accumbens: relevance to feeding reinforcement.},
  author={Andr{\'a}s S{\'a}ndor Hajnal and Gregory P. Mark and Pedro V Rada and L{\'a}szl{\'o} L{\'e}n{\'a}rd and Bartley G. Hoebel},
  journal={Journal of neurochemistry},
  year={1997},
  volume={68 2},
  pages={667-74}
}
Norepinephrine (NE) was microinjected into the paraventricular nucleus (PVN), while microdialysis was used to monitor extracellular dopamine (DA) and acetylcholine (ACh) in the nucleus accumbens (NAc). The PVN is a site where exogenously administered NE can act through alpha 2 receptors to elicit eating behavior and preference for carbohydrates. It was hypothesized that NE in the PVN acts on a behavior reinforcement system by altering the DA/ACh balance in the NAc. NE microinjections (80 nmol… CONTINUE READING

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