Norepinephrine in the rat cortex before and after occlusion of chronic arteriovenous fistulae: a microdialysis study in an animal model of cerebral arteriovenous malformations.

@article{Meyer2002NorepinephrineIT,
  title={Norepinephrine in the rat cortex before and after occlusion of chronic arteriovenous fistulae: a microdialysis study in an animal model of cerebral arteriovenous malformations.},
  author={Bernhard Meyer and Michael F. Stoffel and Carsten Stuer and Carlo Schaller and Bernd Muhlbauer and J. Martinze Schramm},
  journal={Neurosurgery},
  year={2002},
  volume={51 3},
  pages={
          771-9; discussion 779-80
        }
}
OBJECTIVE In an animal model, we tested the hypothesis that intracerebral, extracellular norepinephrine (NE) influences cerebral blood flow (CBF) in the presence of cerebral arteriovenous malformations (AVMs). METHODS A microdialysis (MD) probe was implanted into the cortices of Sprague-Dawley rats 3 months after the creation of extracranial arteriovenous fistulae (AVFs; n = 19), carotid ligation (n = 10), and cervical vessel preparation (sham operations; n = 8). Ipsilateral regional cortical… CONTINUE READING
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