Norepinephrine in septic shock: when and how much?

  title={Norepinephrine in septic shock: when and how much?},
  author={O. Hamzaoui and T. Scheeren and J. Teboul},
  journal={Current Opinion in Critical Care},
  • O. Hamzaoui, T. Scheeren, J. Teboul
  • Published 2017
  • Medicine
  • Current Opinion in Critical Care
  • Purpose of review Norepinephrine is the first-line agent recommended during resuscitation of septic shock to correct hypotension due to depressed vascular tone. Important clinical issues are the best timing to start norepinephrine, the optimal blood pressure target, and the best therapeutic options to face refractory hypotension when high doses of norepinephrine are required to reach the target. Recent findings Recent literature has reported benefits of early administration of norepinephrine… CONTINUE READING
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    • 2
    Early low-dose norepinephrine in patients with septic shock
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    • 5
    Fluid management in the critically ill.
    • 12
    Current use of vasopressors in septic shock
    • 26
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    • 1
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    • 12


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    • 49
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    • 42