Norepinephrine in septic shock: renewed interest in an old drug.

  title={Norepinephrine in septic shock: renewed interest in an old drug.},
  author={Joseph F. Dasta},
  journal={DICP : the annals of pharmacotherapy},
  volume={24 2},
Vasopressors are the mainstay after fluids in the hemodynamic support of patients with septic shock. Although dopamine is commonly used in this situation, it is sometimes ineffective. Because of its potential adverse vasoconstrictive effects, norepinephrine usually has been chosen only when all other drugs have failed in septic shock. However, several recent reports have suggested a beneficial effect of norepinephrine, often in doses higher than those commonly used. Specifically, these studies… CONTINUE READING

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