Norepinephrine ignites local hotspots of neuronal excitation: How arousal amplifies selectivity in perception and memory.

@article{Mather2016NorepinephrineIL,
  title={Norepinephrine ignites local hotspots of neuronal excitation: How arousal amplifies selectivity in perception and memory.},
  author={Mara Mather and David V. Clewett and Michiko Sakaki and Carolyn W. Harley},
  journal={The Behavioral and brain sciences},
  year={2016},
  volume={39},
  pages={
          e200
        }
}
Emotional arousal enhances perception and memory of high-priority information but impairs processing of other information. Here, we propose that, under arousal, local glutamate levels signal the current strength of a representation and interact with norepinephrine (NE) to enhance high priority representations and out-compete or suppress lower priority representations. In our "glutamate amplifies noradrenergic effects" (GANE) model, high glutamate at the site of prioritized representations… CONTINUE READING
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