Noralashinol A, a new norlignan from stem barks of Syringa pinnatifolia.

Abstract

One new norlignan, namely noralashinol A (1), one known analogue (2), together with seven known lignans (3-9) were isolated from the stem barks of Syringa pinnatifolia. Their structures were elucidated extensively by spectroscopic methods, including mass spectrometry and 1D and 2D NMR spectroscopies. Compound 8 significantly inhibited NO production in LPS-induced BV-2 murine microglia cells with its IC50 value of 20.7 μM, compared to a positive control quercetin with its IC50 value of 15.3 μM.

DOI: 10.1080/14786419.2016.1146886

Cite this paper

@article{Su2016NoralashinolAA, title={Noralashinol A, a new norlignan from stem barks of Syringa pinnatifolia.}, author={Guozhu Su and Ruifeng Bai and Xuelong Yu and Yuan Cao and Xu Yin and Pengfei Tu and Xing-yun Chai}, journal={Natural product research}, year={2016}, volume={30 19}, pages={2149-53} }