Noradrenergic dysfunction and the psychopharmacology of posttraumatic stress disorder

@article{Strawn2008NoradrenergicDA,
  title={Noradrenergic dysfunction and the psychopharmacology of posttraumatic stress disorder},
  author={J. Strawn and T. Geracioti},
  journal={Depression and Anxiety},
  year={2008},
  volume={25}
}
The catecholamine norepinephrine is a critical effector of the mammalian stress response and has been implicated in the pathophysiology of posttraumatic stress disorder (PTSD)—a syndrome intrinsically related to the experience of extraordinary stress. Symptom‐linked hypernoradrenergic derangements have been observed in PTSD and several studies have examined the potential therapeutic effects of agents that dampen the centrally hyperactive noradrenergic state. These agents include compounds that… Expand
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