Noradrenergic Locus Coeruleus pathways in pain modulation

@article{LlorcaTorralba2016NoradrenergicLC,
  title={Noradrenergic Locus Coeruleus pathways in pain modulation},
  author={Meritxell Llorca-Torralba and Gisela da Silva Borges and Fani Neto and Juan Antonio Mic{\'o} and Esther Berrocoso},
  journal={Neuroscience},
  year={2016},
  volume={338},
  pages={93-113}
}
The noradrenergic system is crucial for several activities in the body, including the modulation of pain. As the major producer of noradrenaline (NA) in the central nervous system (CNS), the Locus Coeruleus (LC) is a nucleus that has been studied in several pain conditions, mostly due to its strategic location. Indeed, apart from a well-known descending LC-spinal pathway that is important for pain control, an ascending pathway passing through this nucleus may be responsible for the… CONTINUE READING

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