Noradrenaline modulates oyster hemocyte phagocytosis via a beta-adrenergic receptor-cAMP signaling pathway.

@article{Lacoste2001NoradrenalineMO,
  title={Noradrenaline modulates oyster hemocyte phagocytosis via a beta-adrenergic receptor-cAMP signaling pathway.},
  author={Arnaud Lacoste and Shelagh K. Malham and Anne Cueff and Serge Andr{\'e} Poulet},
  journal={General and comparative endocrinology},
  year={2001},
  volume={122 3},
  pages={252-9}
}
Catecholamines (CA) regulate several physiological processes in molluscs. Experiments have been conducted to determine the effects of noradrenaline (NA), the principal CA circulating in bivalve hemolymph, on oyster hemocytephagocytosis. Results show that NA had a dose-dependent inhibitory effect on phagocytosis at physiological concentrations of 0.1 microM and above. The beta-adrenoceptor agonist isoproterenol mimicked the inhibitory effects of NA on phagocytosis, whereas the alpha-adrenoceptor… CONTINUE READING