Noradrenaline induces phosphorylation of ERK-2 in human peripheral blood mononuclear cells after induction of alpha(1)-adrenergic receptors.

Abstract

alpha(1)-Adrenergic receptors (ARs) are not expressed by peripheral blood mononuclear cells (PBMCs) of healthy human individuals. However, in the present study we show that alpha(1)-ARs can be induced in lymphocytes after culturing with either the mitogen PHA or the glucocorticoid dexamethasone. Moreover, incubation of these activated PBMCs with… (More)

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@article{Voort2000NoradrenalineIP, title={Noradrenaline induces phosphorylation of ERK-2 in human peripheral blood mononuclear cells after induction of alpha(1)-adrenergic receptors.}, author={Charlotte Rouppe van der Voort and Annemieke Kavelaars and M. J. van de Pol and Cobi J Heijnen}, journal={Journal of neuroimmunology}, year={2000}, volume={108 1-2}, pages={82-91} }