Noradrenaline, infused locally, reduces arrhythmia severity during coronary artery occlusion in anaesthetised dogs.

@article{Vgh2002NoradrenalineIL,
  title={Noradrenaline, infused locally, reduces arrhythmia severity during coronary artery occlusion in anaesthetised dogs.},
  author={{\'A}gnes V{\'e}gh and James Roy Parratt},
  journal={Cardiovascular research},
  year={2002},
  volume={55 1},
  pages={
          53-63
        }
}
OBJECTIVE To contribute to the debate, discussed in an earlier issue, regarding the role of adrenoceptors in the genesis of early, coronary artery occlusion-induced ventricular arrhythmias. METHODS Mongrel dogs anaesthetised with chloralose and urethane were given either noradrenaline (NA, 100 ng kg(-1) min(-1)), phenylephrine (PHE, 200 ng kg(-1) min(-1)) or isoprenaline (ISO 12.5 ng kg(-1) min(-1)) by intracoronary infusion into a side branch of the left anterior descending coronary artery… CONTINUE READING

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