Nootropic and anxiolytic properties of endogenous ligands of benzodiazepine receptors and their structural analogs

@article{Akhundov1984NootropicAA,
  title={Nootropic and anxiolytic properties of endogenous ligands of benzodiazepine receptors and their structural analogs},
  author={R. A. Akhundov and Tatiana A Voronina},
  journal={Bulletin of Experimental Biology and Medicine},
  year={1984},
  volume={97},
  pages={198-201}
}
Experiments on mice and rats were made to study the nootropic and anxiolytic properties of endogenous ligands of benzodiazepine receptors of nicotinamide and inosin and of their new structural analogs--NMF and AZN. They were shown to have overt antihypoxic and anxiolytic effects. NMF and AZN given in 10-fold lower doses than endogenous benzodiazepine ligands appeared more active than these compounds and almost similar to diazepam as regards the activity. The data obtained point to the… CONTINUE READING