Nonvesicular sterol movement from plasma membrane to ER requires oxysterol-binding protein–related proteins and phosphoinositides

Abstract

Sterols are moved between cellular membranes by nonvesicular pathways whose functions are poorly understood. In yeast, one such pathway transfers sterols from the plasma membrane (PM) to the endoplasmic reticulum (ER). We show that this transport requires oxysterol-binding protein (OSBP)-related proteins (ORPs), which are a large family of conserved lipid… (More)

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@article{Raychaudhuri2006NonvesicularSM, title={Nonvesicular sterol movement from plasma membrane to ER requires oxysterol-binding protein–related proteins and phosphoinositides}, author={Sumana Raychaudhuri and Young Jun Im and James H. Hurley and William A Prinz}, journal={The Journal of Cell Biology}, year={2006}, volume={173}, pages={107 - 119} }