Nonuniform Moving Boundary Method for Computational Fluid Dynamics Simulation of Intrathecal Cerebrospinal Flow Distribution in a Cynomolgus Monkey.

@article{Khani2017NonuniformMB,
  title={Nonuniform Moving Boundary Method for Computational Fluid Dynamics Simulation of Intrathecal Cerebrospinal Flow Distribution in a Cynomolgus Monkey.},
  author={Mohammadreza Khani and Tao Xing and Christina Gibbs and John N. Oshinski and Gregory R. Stewart and Jillynne R. Zeller and Bryn A. Martin},
  journal={Journal of biomechanical engineering},
  year={2017},
  volume={139 8}
}
A detailed quantification and understanding of cerebrospinal fluid (CSF) dynamics may improve detection and treatment of central nervous system (CNS) diseases and help optimize CSF system-based delivery of CNS therapeutics. This study presents a computational fluid dynamics (CFD) model that utilizes a nonuniform moving boundary approach to accurately… CONTINUE READING