Nontypeable Haemophilus influenzae (NTHi) directly interfere with the regulation of E-cadherin in lung epithelial cells.

@article{Kaufhold2017NontypeableHI,
  title={Nontypeable Haemophilus influenzae (NTHi) directly interfere with the regulation of E-cadherin in lung epithelial cells.},
  author={Inga Kaufhold and S{\"u}nja Osbahr and Kensuke Shima and Sebastian Marwitz and Kristina Rohmann and Daniel Dr{\"o}mann and Torsten Goldmann and Klaus Dalhoff and Jan Rupp},
  journal={Microbes and infection},
  year={2017},
  volume={19 11},
  pages={
          560-566
        }
}
Loss of epithelial barriers characterized by reduction of E-cadherin is a hallmark of chronic obstructive pulmonary disease (COPD). We investigated the effects of nontypeable Haemophilus influenzae (NTHi) infections, associated with acute exacerbations of chronic bronchitis, on the regulation of E-cadherin in host cells. NTHi infection decreased E-cadherin… CONTINUE READING