Nontuberculous mycobacteria. II: nested-cohort study of impact on cystic fibrosis lung disease.

@article{Olivier2003NontuberculousMI,
  title={Nontuberculous mycobacteria. II: nested-cohort study of impact on cystic fibrosis lung disease.},
  author={Kenneth N. Olivier and David J. Weber and Ji-Hyun Lee and Allison Handler and Gail Tudor and Paul L. Molina and Joseph F. Tomashefski and Michael R Knowles},
  journal={American journal of respiratory and critical care medicine},
  year={2003},
  volume={167 6},
  pages={835-40}
}
The prevalence of nontuberculous mycobacteria (NTM) is high (approximately 13%) in sputum of patients with cystic fibrosis (CF), but the impact on lung disease is unknown. We followed 60 incident NTM-positive and 99 culture-negative patients with CF for 15 months and assessed clinical impact of NTM by FEV1 and high-resolution computed tomography (HRCT) of the chest. Mycobacterium avium complex was seen in 75% of NTM-positive subjects. The annual rate of decline in FEV1 was not different among… CONTINUE READING

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