Nonsteroidal antiinflammatory drugs reduce radiographic progression in patients with ankylosing spondylitis: a randomized clinical trial.

@article{Wanders2005NonsteroidalAD,
  title={Nonsteroidal antiinflammatory drugs reduce radiographic progression in patients with ankylosing spondylitis: a randomized clinical trial.},
  author={Astrid J B Wanders and D{\'e}sir{\'e}e van der Heijde and Robert L Landew{\'e} and J{\'e}han-Michel B{\'e}hier and Andrei Calin and Ignazio Olivieri and Henning K Zeidler and Maxime R Dougados},
  journal={Arthritis and rheumatism},
  year={2005},
  volume={52 6},
  pages={
          1756-65
        }
}
OBJECTIVE A 2-year randomized controlled trial was performed to test the hypothesis that long-term, continuous treatment with nonsteroidal antiinflammatory drugs (NSAIDs), in comparison with NSAID treatment on demand only, influences radiographic progression in patients with ankylosing spondylitis (AS). METHODS Patients with AS (n = 215), who had previously participated in a 6-week, randomized, double-blind clinical trial that compared celecoxib, ketoprofen, and placebo, were randomly… CONTINUE READING
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