Nonsteroidal antiinflammatory drug use and the risk for Parkinson's disease

  title={Nonsteroidal antiinflammatory drug use and the risk for Parkinson's disease},
  author={H. Chen and E. Jacobs and M. Schwarzschild and M. McCullough and E. Calle and M. Thun and A. Ascherio},
  journal={Annals of Neurology},
  • H. Chen, E. Jacobs, +4 authors A. Ascherio
  • Published 2005
  • Medicine
  • Annals of Neurology
  • We investigated whether nonsteroidal antiinflammatory drug use was associated with a lower risk for Parkinson's disease (PD) in a large cohort of US men and women. PD risk was lower among ibuprofen users than nonusers. Compared with nonusers, the relative risks were 0.73 for users of fewer than 2 tablets/week, 0.72 for 2 to 6.9 tablets/week, and 0.62 for 1 or more tablets/day (p trend = 0.03). No association was found between the use of aspirin, other nonsteroidal antiinflammatory drugs, or… CONTINUE READING
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