Nonsteroidal antiinflammatory drug use and cognitive function in the elderly: inconclusive results from a population-based cohort study.

@article{Fourrier1996NonsteroidalAD,
  title={Nonsteroidal antiinflammatory drug use and cognitive function in the elderly: inconclusive results from a population-based cohort study.},
  author={Annie Fourrier and L Letenneur and Bernard B{\'e}gaud and Jean François Dartigues},
  journal={Journal of clinical epidemiology},
  year={1996},
  volume={49 10},
  pages={
          1201
        }
}
As part of the cohort Paquid, we studied the relationship between the use of NSAID, incidence of dementia, and evolution of cognitive functions. Dementia was diagnosed by DSM-III criteria and cognitive functions was assessed through the Mini-Mental Status Examination (MMSE). During 2 years of follow-up, the incidence rate of dementia was 3.84% among 53 NSAID users as compared with 3.77% in 1199 nonusers (OR, 0.98; 95% CI, 0.23-4.16). Using a cutoff of -3 points for the MMSE score and taking… CONTINUE READING
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