Nonsteroidal anti-inflammatory drugs and inflammatory bowel disease: pathophysiology and clinical associations.

Abstract

Nonsteroidal anti-inflammatory drugs (NSAIDs) produce significant gastrointestinal (GI) adverse events. Laboratory and clinical studies suggest that NSAIDs have the potential to trigger the onset or relapse of inflammatory bowel disease. In this review, the currently available information on the mechanism of action of NSAID injury of the GI tract and the… (More)
DOI: 10.1097/MIB.0000000000000165

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