Nonsteroidal anti-inflammatory drug use and serum total estradiol in postmenopausal women.

@article{Hudson2008NonsteroidalAD,
  title={Nonsteroidal anti-inflammatory drug use and serum total estradiol in postmenopausal women.},
  author={Alana G Hudson and Gretchen L. Gierach and Francesmary Modugno and Jennifer Simpson and John Wilson and Rhobert Wyn Evans and Victor G. Vogel and Joel L. Weissfeld},
  journal={Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology},
  year={2008},
  volume={17 3},
  pages={680-7}
}
Laboratory and epidemiologic evidence suggest that nonsteroidal anti-inflammatory drug (NSAID) use may be inversely related to the risk of breast cancer; however, the mechanism by which NSAIDs may protect against the development of this disease is uncertain. The objective of this observational study was to assess the relationship between current NSAID use and endogenous estradiol levels, an established breast cancer risk factor. To evaluate this aim, we conducted a cross-sectional investigation… CONTINUE READING

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