Nonsteroidal anti-inflammatory drug-induced hepatotoxicity.

@article{Aithal2007NonsteroidalAD,
  title={Nonsteroidal anti-inflammatory drug-induced hepatotoxicity.},
  author={Guruprasad P Aithal and Christopher Paul Day},
  journal={Clinics in liver disease},
  year={2007},
  volume={11 3},
  pages={
          563-75, vi-vii
        }
}
Nonsteroidal anti-inflammatory drugs are among the most common drugs associated with drug-induced liver injury, with an estimated incidence of between 3 and 23 per 100,000 patient years. Nimesulide, sulindac, and diclofenac seem to be associated with the highest risk and the only risk factor consistently identified is the concomitant use of other hepatotoxic drugs. Diclofenac-induced liver injury is a paradigm for drug-related hepatotoxicity. Recent studies suggest that genetic factors favoring… CONTINUE READING
BETA

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-10 OF 46 CITATIONS

Piroxicam- Induced Hepatotoxicity

VIEW 1 EXCERPT
CITES BACKGROUND

Safety assessment of vitacoxib: 180-day chronic oral toxicity studies.

  • Regulatory toxicology and pharmacology : RTP
  • 2018
VIEW 1 EXCERPT
CITES BACKGROUND