Nonsteroidal anti-inflammatory drug-associated gastropathy: incidence and risk factor models.

@article{Fries1991NonsteroidalAD,
  title={Nonsteroidal anti-inflammatory drug-associated gastropathy: incidence and risk factor models.},
  author={James F. Fries and Carol Williams and Daniel A. Bloch and Beat Michel},
  journal={The American journal of medicine},
  year={1991},
  volume={91 3},
  pages={213-22}
}
PURPOSE The most prevalent serious drug toxicity in the United States is increasingly recognized as gastrointestinal (GI) pathology associated with the use of nonsteroidal anti-inflammatory drugs (NSAIDs). The incidence of serious GI events (hospitalization or death) associated with NSAID use was therefore prospectively analyzed in patients with rheumatoid arthritis (RA) and patients with osteoarthritis. PATIENTS, METHODS, AND RESULTS The study consisted of 2,747 patients with RA and 1,091… CONTINUE READING

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