Nonsteroidal Anti-Inflammatory Drugs and Heart Failure

@article{Bleumink2012NonsteroidalAD,
  title={Nonsteroidal Anti-Inflammatory Drugs and Heart Failure},
  author={Gys{\`e}le S. Bleumink and Johannes Feenstra and Miriam Sturkenboom and Bruno H. Stricker},
  journal={Drugs},
  year={2012},
  volume={63},
  pages={525-534}
}
Heart failure constitutes an increasing public health problem because of the growing incidence and prevalence, poor prognosis and high hospital (re)admission rates. Myocardial infarction is the underlying cause in the majority of patients, followed by hypertension, valvular heart disease and idiopathic cardio-myopathy.Nonsteroidal anti-inflammatory drugs (NSAIDs), which inhibit the enzymes cyclo-oxygenase (COX) 1 and 2, have been associated with the occurrence of symptoms of heart failure in… 
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