Nonspecific esterases of leukemia cell lines: evidence for activation of myeloid-associated zymogens in HL-60 by phorbol esters.

@article{Yourno1984NonspecificEO,
  title={Nonspecific esterases of leukemia cell lines: evidence for activation of myeloid-associated zymogens in HL-60 by phorbol esters.},
  author={Joseph Yourno and James M. Walsh and G Kornatowski and Dennis O'connor and S. R. Anand Kumar},
  journal={Blood},
  year={1984},
  volume={63 1},
  pages={238-41}
}
Myeloid leukemia cell line HL-60 contains fluoride-sensitive, myeloid-associated isoenzymes of nonspecific esterase that increase in activity when cultures are treated with phorbol ester. These isoenzymes are not detectable in B-lymphoblast cell line KLM-2, either in control or in phorbol-ester-treated cultures. No increased de novo synthesis of the… CONTINUE READING