Nonsegmented negative-strand RNA viruses: genetics and manipulation of viral genomes.

@article{Conzelmann1998NonsegmentedNR,
  title={Nonsegmented negative-strand RNA viruses: genetics and manipulation of viral genomes.},
  author={Karl-Klaus Conzelmann},
  journal={Annual review of genetics},
  year={1998},
  volume={32},
  pages={
          123-62
        }
}
  • K. Conzelmann
  • Published 1 December 1998
  • Biology
  • Annual review of genetics
Protocols to recover negative-stand RNA viruses entirely from cDNA have been established in recent years, opening up this virus group to the detailed analysis of molecular genetics and virus biology. The unique gene-expression strategy of nonsegmented negative-strand RNA viruses, which involves replication of ribonucleoprotein complexes and sequential synthesis of free mRNAs, has also allowed the use of these viruses to express heterologous sequences. There are advantages in terms of easy… 
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