Nonrandom HIV-1 infection and double infection via direct and cell-mediated pathways.

@article{Dang2004NonrandomHI,
  title={Nonrandom HIV-1 infection and double infection via direct and cell-mediated pathways.},
  author={Que Anh Dang and Jianbo Chen and Derya Unutmaz and John M Coffin and Vinay K Pathak and Douglas Powell and Vineet N Kewalramani and Frank M Maldarelli and Wei-Shau Hu},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2004},
  volume={101 2},
  pages={632-7}
}
Cells infected with two related retroviruses can generate heterozygous virions, which are the precursors of recombinant proviruses. Although many studies have focused on the frequencies and mechanisms of retroviral recombination, little is known about the dynamics of double infection. To examine this issue, viruses generated from two HIV-1 vectors containing different markers were mixed together, and were used to infect target cells. The numbers of cells expressing none, one, or both markers… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 48 extracted citations

Similar Papers

Loading similar papers…