Nonparametric estimation of lifetime and disease onset distributions from incomplete observations.

@article{Dinse1982NonparametricEO,
  title={Nonparametric estimation of lifetime and disease onset distributions from incomplete observations.},
  author={Gregg E. Dinse and Stephen W Lagakos},
  journal={Biometrics},
  year={1982},
  volume={38 4},
  pages={921-32}
}
In this paper we derive and investigate nonparametric estimators of the distributions of lifetime and time until onset associated with an irreversible disease that is detectable only at death. The nonparametric maximum likelihood solution requires an iterative algorithm. An alternative though closely related pair of estimators for the lifetime and onset distributions exists in closed form. These estimators are the familiar Kaplan-Meier estimator and an isotonic regression estimator… CONTINUE READING

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