Nonparametric and semiparametric group sequential methods for comparing accuracy of diagnostic tests.

@article{Tang2008NonparametricAS,
  title={Nonparametric and semiparametric group sequential methods for comparing accuracy of diagnostic tests.},
  author={Liansheng Larry Tang and Scott S. Emerson and Xiao-Hua Zhou},
  journal={Biometrics},
  year={2008},
  volume={64 4},
  pages={
          1137-45
        }
}
SUMMARY Comparison of the accuracy of two diagnostic tests using the receiver operating characteristic (ROC) curves from two diagnostic tests has been typically conducted using fixed sample designs. On the other hand, the human experimentation inherent in a comparison of diagnostic modalities argues for periodic monitoring of the accruing data to address many issues related to the ethics and efficiency of the medical study. To date, very little research has been done on the use of sequential… CONTINUE READING

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