Nonoperative approaches to rectal cancer: a critical evaluation.

  title={Nonoperative approaches to rectal cancer: a critical evaluation.},
  author={Angelita Habr-Gama and R O Perez and Guilherme Pagin S{\~a}o Juli{\~a}o and Igor Proscurshim and Joaquim Jos{\'e} Gama-Rodrigues},
  journal={Seminars in radiation oncology},
  volume={21 3},
A neoadjuvant multimodality approach with chemoradiation therapy (CRT) is the preferred treatment strategy for most distal rectal cancers. Significant downstaging and complete pathologic response may develop after this strategy, and there is still controversy regarding the management of these patients. In this setting, a nonoperative approach has been suggested in select patients with complete clinical response after thorough clinical, endoscopic, and radiologic assessment. However, the… CONTINUE READING


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Long - term outcome in patients with a pathological complete response after chemoradiation for rectal cancer : A pooled analysis of individual patient data

  • A Habr-Gama, RO Perez, G Wynn
  • Lancet Oncol
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Pathologic complete response ( pCR ) to neoadjuvant chemoradiation ( CRT ) of uT 2 uN 0 rectal cancer ( RC ) treated by local excision ( LE ) : Results of the ACOSOG Z 6041 trial

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