Nonomuraea sp. ATCC 55076 harbours the largest actinomycete chromosome to date and the kistamicin biosynthetic gene cluster† †The authors declare no competing interests. ‡ ‡Electronic supplementary information (ESI) available. See DOI: 10.1039/c6md00637j Click here for additional data file.

@inproceedings{Nazari2017NonomuraeaS,
  title={
Nonomuraea sp. ATCC 55076 harbours the largest actinomycete chromosome to date and the kistamicin biosynthetic gene cluster†
†The authors declare no competing interests.
‡
‡Electronic supplementary information (ESI) available. See DOI: 10.1039/c6md00637j
Click here for additional data file.

},
  author={Behnam Nazari and Clarissa C Forneris and Marcus I. Gibson and Kyuho Moon and Kelsey R. Schramma and Mohammad R Seyedsayamdost},
  booktitle={MedChemComm},
  year={2017}
}
Glycopeptide antibiotics (GPAs) have served as potent clinical drugs and as an inspiration to chemists in various disciplines. Among known GPAs, complestatin, chloropeptin, and kistamicin are unique in that they contain an unusual indole-phenol crosslink. The mechanism of formation of this linkage is unknown, and to date, the biosynthetic gene cluster of only one GPA with an indole-phenol crosslink, that of complestatin, has been identified. Here, we report the genome sequence of the kistamicin… CONTINUE READING