Nonneutralizing antibody against the glycoprotein K of herpes simplex virus type-1 exacerbates herpes simplex virus type-1-induced corneal scarring in various virus-mouse strain combinations.

@article{Ghiasi1997NonneutralizingAA,
  title={Nonneutralizing antibody against the glycoprotein K of herpes simplex virus type-1 exacerbates herpes simplex virus type-1-induced corneal scarring in various virus-mouse strain combinations.},
  author={Homayon Ghiasi and Steve Cai and Susan M Slanina and Anthony B. Nesburn and Steven L Wechsler},
  journal={Investigative ophthalmology & visual science},
  year={1997},
  volume={38 6},
  pages={1213-21}
}
PURPOSE To determine whether the exacerbation of herpes simplex virus type-1 (HSV-1) induced corneal scarring that the authors reported previously in HSV-1 glycoprotein K (gK) vaccinated BALB/c mice challenged with HSV-1 strain McKrae was a general phenomenon independent of virus and mouse strains. To determine the gK-induced immune response leading to exacerbation of HSV-1-induced corneal scarring. METHODS BALB/c or C57BL/6 mice were vaccinated with gK, ocularly challenged with HSV-1 strain… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 53 references

HSV turns of the TAP to evade host immunity

  • A Hill, P Jugovic, G Russ
  • Nature (London)
  • 1995

Protection against HSV induced eye disease following vaccination with 7 individually expressed HSV-1 glycoproteins

  • H Ghiasi, S Bahri, R Kaiwar, AB Nesburn, S Slanina, SL. Wechsler
  • Invest Ophthalmol Vis Sci
  • 1995

Similar Papers

Loading similar papers…