Nonmyeloablative allogeneic stem cell transplant strategies and the role of mixed chimerism.

@article{Spitzer2000NonmyeloablativeAS,
  title={Nonmyeloablative allogeneic stem cell transplant strategies and the role of mixed chimerism.},
  author={Thomas R. Spitzer},
  journal={The oncologist},
  year={2000},
  volume={5 3},
  pages={215-23}
}
Experimental and clinical experiences have demonstrated successsful donor engraftment following nonmyeloablative preparative regimens. These less toxic conditioning strategies may be better tolerated with diminished transplant-related morbidity and mortality. Importantly, the intentional induction of mixed chimerism can be established following nonmyeloablative conditioning. This approach has the potential advantages of inhibiting graft-versus-host disease, presumably secondary to the… CONTINUE READING
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Collection of bone marrow

  • T. Spitzer
  • Cellular Therapies: A Clinical Laboratory…
  • 1999

Outpatient allografting with minimal myelosuppressive , immunosuppressive conditioning of low dose TBI and postgrafting cyclosporine ( CSP ) and mycophenolate mofetil ( MMF )

  • P McSweeney, D Niederwieser, J Shizuru
  • Blood
  • 1999

Outpatient allografting with minimal myelosuppressive, immunosuppressive conditioning of low dose TBI and postgrafting cyclosporine (CSP) and mycophenolate mofetil (MMF). Blood 1999;94:393a

  • P McSweeney, D Niederwieser, J Shizuru
  • 1999

Reduced toxicity and transplant related mortality (TRM) following non-myeloablative allogeneic peripheral blood stem cell transplantation for malignant diseases

  • R Childs, E Clave, N Contentin
  • Blood
  • 1999

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