Nonmuscle myosin IIB regulates epicardial integrity and epicardium-derived mesenchymal cell maturation.

Abstract

Nonmuscle myosin IIB (NMIIB; heavy chain encoded by MYH10) is essential for cardiac myocyte cytokinesis. The role of NMIIB in other cardiac cells is not known. Here, we show that NMIIB is required in epicardial formation and functions to support myocardial proliferation and coronary vessel development. Ablation of NMIIB in epicardial cells results in… (More)
DOI: 10.1242/jcs.202564

Topics

Cite this paper

@article{Ma2017NonmuscleMI, title={Nonmuscle myosin IIB regulates epicardial integrity and epicardium-derived mesenchymal cell maturation.}, author={Xuefei Ma and Derek C Sung and Yanqin Yang and Yoshi Wakabayashi and Robert S Adelstein}, journal={Journal of cell science}, year={2017}, volume={130 16}, pages={2696-2706} }