Nonmotor predictors for levodopa requirement in de novo patients with Parkinson's disease.


The variability in the clinical phenotype of Parkinson's disease (PD) suggests the existence of several subtypes of the disease. Motor heterogeneity of PD is well established, but not nonmotor heterogeneity. At present, we are unable to predict the rate of progression of PD based on robust biomarkers. We aimed to examine the heterogeneity of PD by… (More)
DOI: 10.1002/mds.26076