Nonmetastatic intracranial germinoma: the experience of the French Society of Pediatric Oncology.

@article{Baranzelli1997NonmetastaticIG,
  title={Nonmetastatic intracranial germinoma: the experience of the French Society of Pediatric Oncology.},
  author={Marie Christine Baranzelli and Catherine Patte and Eric Bouffet and D. Valteau Couanet and Jean Louis Habrand and Matt Portas and Odile Lejars and Patrick Lutz and E le Gall and Chantal Kalifa},
  journal={Cancer},
  year={1997},
  volume={80 9},
  pages={1792-7}
}
BACKGROUND Standard treatment of localized intracranial germinoma is focal irradiation of the primary tumor (45-50 grays [Gy]) combined with craniospinal radiotherapy (RT). To decrease late effects related to extensive fields of RT, the French Society of Pediatric Oncology decided in 1990 to replace prophylactic RT with chemotherapy (CT) and to deliver focal RT at 40 Gy. METHODS Twenty-nine patients with localized, biopsy proven germinoma were included in this study between January 1990 and… CONTINUE READING