Nonlinkage of major histocompatibility complex class I and class II loci in bony fishes

Abstract

 In tetrapods, the functional (classical) class I and class II B loci of the major histocompatibility complex (Mhc) are tightly linked in a single chromosomal region. In an earlier study, we demonstrated that in the zebrafish, Danio rerio, order Cypriniformes, the two classes are present on different chromosomes. Here, we show that the situation is similar… (More)
DOI: 10.1007/s002510050019

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