Nonlinearity and harmonic distortion of dog lungs measured by low-frequency forced oscillations.

@article{Suki1991NonlinearityAH,
  title={Nonlinearity and harmonic distortion of dog lungs measured by low-frequency forced oscillations.},
  author={B{\'e}la Suki and Zolt{\'a}n Hantos and B. Dar{\'o}czy and G Alkaysi and Sandor Nagy},
  journal={Journal of applied physiology},
  year={1991},
  volume={71 1},
  pages={69-75}
}
The nonlinearity of lung tissues and airways was studied in six anesthetized and paralyzed open-chest dogs by means of 0.1-Hz sinusoidal volume forcing at mean transpulmonary pressures (Ptp) of 5 and 10 cmH2O. Lung resistance (RL) and elastance (EL) were determined in a 32-fold range (15-460 ml) of tidal volume (VT), both by means of spectrum analysis at the fundamental frequency and with conventional time-domain techniques. Alveolar capsules were used to separate the tissue and airway… CONTINUE READING

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